发明名称 Anticholinergic bronchodilators
摘要 Compounds of the formula <IMAGE> I where R1 and R2 are the same or different and are C1 to C6 alkyl; C5 or C6 cycloalkyl; C5 or C6 cycloalkenyl; phenyl optionally substituted with a substitutent selected from the group C1 to C6 alkyl, C1 to C6 alkoxy and halo; or C4 or C5 heterocyclic aryl, the heteroatom selected from the group oxygen, nitrogen and sulfur; Y is the radical selected from (CH2)n, (C4H8S), (C4H8O) and <IMAGE> where R is hydrogen or C1 to C6 alkyl and n is the integer 4 or 5; and X is selected from the group methanesulfonate, benzenesulfonate, p-toluenesulfonate, nitrate, chloride, bromide and iodide. Methods for preparing these compounds are also disclosed. The compounds of the present invention are useful as anticholinergic agents.
申请公布号 US4208423(A) 申请公布日期 1980.06.17
申请号 US19780963258 申请日期 1978.11.24
申请人 SYNTEX (U S A) INC 发明人 PFISTER, JURG R
分类号 A61K31/40;A61P11/08;C07D207/12;C07D471/10;C07D487/10;(IPC1-7):A61K31/40 主分类号 A61K31/40
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