发明名称 |
Stable aqueous solutions of glucans and glucan derivatives capable of inhibiting sarcoma in mice |
摘要 |
The glucans and glucan derivatives which inhibit the growth of sarcoma 180 in mice are only sparingly soluble in water, and their aqueous solutions are unstable. In the presence of 0.1 to 1.0 g/dl water soluble dextran, hydroxyethyl starch, carboxymethyl cellulose, or polyethylene glycol, they form relatively concentrated and stable solutions, particularly in the presence of hexoses, pentoses or sugar alcohols having 5 or 6 carbon atoms.
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申请公布号 |
US4207312(A) |
申请公布日期 |
1980.06.10 |
申请号 |
US19760654452 |
申请日期 |
1976.02.02 |
申请人 |
AJINOMOTO CO INC;MORISHITA PHARMACEUTICALS CO LTD |
发明人 |
FUJII, MITSUHARU;HAMURO, JUNJI;IWAO, YUTAKA;KUOKA, TATSUO;SETSUTA, TATSUO;SHIIO, TSUYOSHI;YOSHIHAMA, TAKASHI;YUGARI, YASUMI |
分类号 |
A61K31/715;A61K9/08;A61K36/07;A61K47/26;A61K47/36;A61K47/38;(IPC1-7):A61K31/70;A61K31/00 |
主分类号 |
A61K31/715 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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