摘要 |
The invention comprises O-nicotinoylcholine halides, their hydrohalide salts and their preparation by reacting a b -haloethyl ester of nicotinic acid with trimethylamine, reacting a methyl halide with nicotinic acid N,N-dimethyl-amino ethyl ester and by reacting a choline halide with a source of nicotinoyl radicals and where O-nicotinoylcholine iodide is produced, optionally converting the latter into the corresponding chloride by reaction with silver chloride. The compounds of the invention have vasodilating properties. |