发明名称 |
CEPHALOSPORIN COMPOUNDS |
摘要 |
A process for the preparation of a 3-carbamoyloxymethyl cephalosporin compound which comprises reacting a 3-hydroxymethyl cephalosporin with dihalophosphinyl isocyanate and converting the resulting 3-phosphonocarbamoyloxymethyl cephalosporin reaction product by hydrolysis to the desired compound. The isocyanates used in the process are readily available and easy to handle and thus the process avoids the use of hazardous and/or expensive reagents. |
申请公布号 |
ZA7901653(B) |
申请公布日期 |
1980.05.28 |
申请号 |
ZA19790001653 |
申请日期 |
1979.04.06 |
申请人 |
GLAXO GROUP LTD |
发明人 |
HUMBER D;WEINGARTEN G;LAING S |
分类号 |
A61K31/545;A61K31/546;A61P31/04;C07D501/04;C07D501/26;C07D501/57;C07D501/60;C07F9/6561 |
主分类号 |
A61K31/545 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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