| 摘要 |
NEW MATERIAL:A penicillin analog of formula I (R1-3 are organic or inorganic residues). EXAMPLE:p-Methoxybenzyl 3-cyano- 3 -methyl- 7 -oxo- 6 -phenylacetamido- 4 -thia- 1-azabicyclo-[3,2,0]heptane-2-carboxylate. USE:Antibacterial agent and its intermediate. PROCESS:The compound I is prepared by heating a 2-azido-2-cephem compound II in an inert solvent such as benzene and toluene, at 50-150 deg.C, pref. 70-120 deg.C. |
