| 摘要 |
Soft quaternary surface active agents having the formula: <IMAGE> (I) <IMAGE> (II) wherein >N represents a tertiary open chain or cyclic aliphatic amine; wherein >N represents an unsaturated amine; wherein R represents a member selected from the group consisting of a hydrogen atom, a C1-C20 open chain or cyclo alkyl group, a C1-C20 alkoxyalkyl group, a C1-C20 acyloxyalkyl group, a C1-C20 haloalkyl group, a C1-C20 carboxyalkyl group, an aryl group, and a substituted aryl group, whose substituents are selected from the group consisting of a halogen atom, an O-C1-C4 alkyl group, an O-C1-C8 acyl group, a nitro group, a carboxyl group, and a carboethoxy group; wherein R1 represents a C9-C22 straight or branched alkyl group, a -(CH2)n- <IMAGE> group, wherein R3, R4, R5 and R6 are each selected from the group consisting of a hydrogen atom, a methyl group or an ethyl group, a C0-C22 straight or branched alkyl-(CH2)n <IMAGE> (CH2)mCH3 group, wherein n in each occurrence and m represents an integer of from 0 to 22, an A-CH2 <IMAGE> CH2-A-CH3 group, wherein A represents a C0-C22 straight or branched alkyl group as above or a -(CH2CH2O) group, wherein the p represents an integer of from 0 to 22, and the residue of any naturally occurring bile acid or synthetic derivative thereof; and wherein X represents a halogen atom or any other organic or inorganic monovalent anion are disclosed. All compounds encompassed within the above-described generic formulae find use as "soft" antibacterial agents of extremely low toxicity.
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