4-Hydroxy-2-pyrone derivatives, process for their preparation and their pharmaceutical preparations.

摘要

4-Hydroxy-2-pyrone derivatives of formula (I):
<Chemistry id="chema01" num="0001"><Image id="ia01" he="25" wi="54" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>(wherein A represents an alkylene group which is optionally alkyl-substituted or an alkenylene group, and Z represents a substituted or unsubstituted aryl or aryloxy group) may be prepared by cyclizing an ester of formula (II):
<Chemistry id="chema02" num="0002"><Image id="ia02" he="15" wi="67" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>(wherein A and Z are as defined above and R represents an organic group) and have valuable antilipaemic activities.