(S)-1-[2-(4-(2-Hydroxy-s-(1-alkylaminopropoxy)phenylalkyl]-4-phenylpiperazines

摘要

There are disclosed compounds of the formula <IMAGE> wherein R1 is selected from the group consisting of lower alkyl; R8 is selected from the group consisting of -O-(CH2)n-wherein n is 2 to 20, <IMAGE> and R6 is selected from the group consisting of hydrogen or lower alkoxy, and <IMAGE> wherein R1 is selected from the group consisting of lower alkyl; R8 is selected from the group consisting of -O-(CH2)n-wherein n is 2 to 20, <IMAGE> and R6 is selected from the group consisting of hydrogen or lower alkoxy and racemates thereof. There are also disclosed processes and intermediates utilized to produce the end products. The end products have utility as agents exhibiting both alpha and selective beta adrenergic blocking action.