发明名称 DERIVATIVES OF CLAVULANIC ACID
摘要 The invention provides the compound of the formula (I): <CHEM> wherein R is a hydrogen atom or a methyl, methoxyl, hydroxymethyl or nitrile group; R<1> is a hydrogen atom or a lower alkyl, aralkyl, phenyl or inertly substituted lower alkyl, aralkyl or phenyl group; R<2> is a hydrogen atom or a lower alkyl, aralkyl, phenyl or inertly substituted lower alkyl, aralkyl or phenyl group; and R<3> is lower alkyl, aralkyl, phenyl or inertly substituted lower alkyl, aralkyl or phenyl group; any of said groups R<1>, R<2> and R<3> being optionally interlinked to form a ring of 5-7 atoms. These compounds are useful as anti-bacterial agents, ss-lactamase inhibitors and chemical intermediates. Their preparation is described.
申请公布号 AU4121778(A) 申请公布日期 1980.05.08
申请号 AU19780041217 申请日期 1978.10.31
申请人 BEECHAM GROUP LTD. 发明人 MICHAEL LIBERMAN;KENNETH THOMAS VEAL;JOHN MARTIN TEDDER;KENNETH RICHARDSON
分类号 A61K31/42;A61P31/04;C07D503/00 主分类号 A61K31/42
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