发明名称 Indole derivatives and therapeutically acting drugs
摘要 The invention relates to new indole derivatives, their preparation and use as drugs. Said compounds may be represented by the general formula <IMAGE> (I) in which R represents a hydrogen atom or an alkyl or benzyl group and Z represents a hydrogen atom or a halogen atom or an alkyl, hydroxy, acyloxy, carbamate or methoxy group. They are prepared by reacting tryptamine derivatives with synthons of the formula <IMAGE> (V) in which X and Y each represent an oxygen or sulphur atom, and R1 and R2 each represent an alkyl or phenyl radical or form together an alkylidene chain. They may be used as intermediate compounds for chemical syntheses and also as drug for treating cerebro-vascular and cardio-circulatory insufficiencies.
申请公布号 US4200638(A) 申请公布日期 1980.04.29
申请号 US19780946456 申请日期 1978.09.27
申请人 OMNIUM CHIMIQUE S.A. 发明人 HANNART, JEAN A A J
分类号 A61K31/435;A61P9/00;A61P9/08;C07D471/04;C07D471/16;(IPC1-7):A61K31/44 主分类号 A61K31/435
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