发明名称 Enlarged-hetero-ring prostacyclin analogs
摘要 Prostaglandin (PG1) derivatives having (1) a 6-keto feature, together with a 9-deoxy-9-hydroxymethyl feature for example <IMAGE> or (2) a 9-deoxy-6,9-epoxymethano feature together with a 5-halo or 6-hydroxy feature, for example <IMAGE> or <IMAGE> or a 5,6-didehydro feature, for example in an enol ether of the formula <IMAGE> said derivatives having pharmacological activity. Processes for preparing them and the appropriate intermediates are disclosed.
申请公布号 US4200739(A) 申请公布日期 1980.04.29
申请号 US19780935392 申请日期 1978.08.21
申请人 UPJOHN CO THE 发明人 KELLY, ROBERT C
分类号 C07C405/00;C07D311/94;(IPC1-7):C07D311/02 主分类号 C07C405/00
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