发明名称 1-(TRIALKYLAMINO)-3-(PHENYLPHENOXY)-2-PROPANOL QUARTERNARY SALTS
摘要 <p>1-(Trialkylamino)-3-phenylphenoxy-2-propanol quarternary salts are described herein. They exhlbit potent and long-acting anti-arrhythmic activity while lacking the undesirable side-effects, e.g. .beta.-andregenic receptor blocking activity and local anesthetic activity characteristic of prior art compounds. The compounds of this invention are prepared by contacting the appropriate tertiary amine with an alkyl halide, alkyl sulfate or alkyl phosphate.</p>
申请公布号 CA1076605(A) 申请公布日期 1980.04.29
申请号 CA19760263714 申请日期 1976.10.19
申请人 REGENTS OF THE UNIVERSITY OF MICHIGAN (THE) 发明人 COUNSELL, RAYMOND E.;LUCCHESI, BENEDICT R.
分类号 A61K31/13;A61P9/06;C07C67/00;C07C213/00;C07C217/32;C07D303/22;(IPC1-7):07C93/14 主分类号 A61K31/13
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