发明名称 PROCESS FOR PREPARING 17ALPHA-HYDROXY-PREGNAN-20-ONE DERIVATIVES
摘要 A process for the preparation of pregnane derivatives of the formula <IMAGE> wherein R1 is methyl or ethyl and R2 is methyl, ethyl, formyl, or acetyl, comprises reacting a nitrate ester of the formula <IMAGE> wherein R1 is as above, in the presence of a catalytic amount of a mercury salt of a lower carboxylic acid with formic acid or acetic acid in a dipolar aprotic or basic solvent or with methanol or ethanol in an aprotonic, especially water-miscible, solvent in the presence of a mineral acid.
申请公布号 HU174982(B) 申请公布日期 1980.04.28
申请号 HU1977SE00609 申请日期 1977.06.01
申请人 SCHERING AG,WB,DE 发明人 HOFMEISTER,HELMUT,WB;ANNEN,KLAUS,WB;LAURENT,HENRY,WB;WIECHERT,RUDOLF,WB
分类号 C07J7/00;C07J41/00 主分类号 C07J7/00
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