发明名称 |
PROCESS FOR PREPARING 17ALPHA-HYDROXY-PREGNAN-20-ONE DERIVATIVES |
摘要 |
A process for the preparation of pregnane derivatives of the formula <IMAGE> wherein R1 is methyl or ethyl and R2 is methyl, ethyl, formyl, or acetyl, comprises reacting a nitrate ester of the formula <IMAGE> wherein R1 is as above, in the presence of a catalytic amount of a mercury salt of a lower carboxylic acid with formic acid or acetic acid in a dipolar aprotic or basic solvent or with methanol or ethanol in an aprotonic, especially water-miscible, solvent in the presence of a mineral acid. |
申请公布号 |
HU174982(B) |
申请公布日期 |
1980.04.28 |
申请号 |
HU1977SE00609 |
申请日期 |
1977.06.01 |
申请人 |
SCHERING AG,WB,DE |
发明人 |
HOFMEISTER,HELMUT,WB;ANNEN,KLAUS,WB;LAURENT,HENRY,WB;WIECHERT,RUDOLF,WB |
分类号 |
C07J7/00;C07J41/00 |
主分类号 |
C07J7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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