CLAVULANIC ACID ESTERS

摘要

A new antibacterially active agent has been isolated from Streptomyces clavuligerus. This new compound which we designate clavulanic acid has the formula (I): (I) In addition to being a broad spectrum antibiotic of medium potency, clavulanic acid and its salts and esters have the ability to enhance the effectiveness of .beta.-lactam antibiotics against many .beta.-lactamase producing bacteria.