| 摘要 |
<p>This invention relates to compositions for carrying physiologically active agents through body membranes. Many physiologically active agents are best applied topically to obtain desirable results. The greatest problem in applying physiologically active agents topically is that the skin is such an effective barrier to penetration. Vehicles such as USP cold cream, ethanol and various ointments, oils, solvents, and emulsions have been used heretofore to apply physiologically active ingredients locally. Most such vehicles are not effective to carry significant amounts of physiologically active agents through the skin. The present invention relates to compositions useful in topically administering a physiologically active agent to a human or animal comprising the agent and an effective, non-toxic amount of a compound having the structural formula Where R' is H or a lower alkyl group having 1-4 carbon atoms, m is 3-7,n is 0-17, and R is -CH3 , or where R" = H or Halogen and R' has the same meaning as above, with the provisio that if m + 3 and R + -CH3 then n is no 0-4.</p> |
