发明名称 Substituted anthracyclines, their preparation and use
摘要 Compounds having the formula: <IMAGE> wherein (a) when R1 is -COCH3 or -COCH2OH, R2 is -OH, R3 is -OCH3 and R4 is -H; (b) when R2 is -COCH3 or -COCH2OH; R1 is -OH, R3 is -H and R4 is -OCH3; and which are useful in treating certain mammalian tumors, are prepared from 9,10-anhydro-N-trifluoroacetyl daunorubicin, a known compound.
申请公布号 US4199571(A) 申请公布日期 1980.04.22
申请号 US19780941847 申请日期 1978.09.13
申请人 FARMITALIA CARLO ERBA SPA 发明人 ANGELUCCI, FRANCESCO;ARCAMONE, FEDERICO;GOZZI, FAUSTO;PENCO, SERGIO
分类号 A61K31/70;A61K31/7028;A61K31/7034;A61K31/704;A61P35/00;C07D303/32;C07D319/08;C07H15/252;(IPC1-7):A61K31/71;C07H15/24 主分类号 A61K31/70
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