发明名称 |
Substituted anthracyclines, their preparation and use |
摘要 |
Compounds having the formula: <IMAGE> wherein (a) when R1 is -COCH3 or -COCH2OH, R2 is -OH, R3 is -OCH3 and R4 is -H; (b) when R2 is -COCH3 or -COCH2OH; R1 is -OH, R3 is -H and R4 is -OCH3; and which are useful in treating certain mammalian tumors, are prepared from 9,10-anhydro-N-trifluoroacetyl daunorubicin, a known compound.
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申请公布号 |
US4199571(A) |
申请公布日期 |
1980.04.22 |
申请号 |
US19780941847 |
申请日期 |
1978.09.13 |
申请人 |
FARMITALIA CARLO ERBA SPA |
发明人 |
ANGELUCCI, FRANCESCO;ARCAMONE, FEDERICO;GOZZI, FAUSTO;PENCO, SERGIO |
分类号 |
A61K31/70;A61K31/7028;A61K31/7034;A61K31/704;A61P35/00;C07D303/32;C07D319/08;C07H15/252;(IPC1-7):A61K31/71;C07H15/24 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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