发明名称 |
ANTITHROMBOTIC COMPOSITIONS |
摘要 |
This invention relates to a pharmaceutical composition useful in the treatment of arterial thrombosis. A combination of a non-steroidal anti-inflammatory agent with a benzisothiazolone of formula (I) is found to be capable of inhibiting the aggregation of blood platelets to a greater degree than each of the components separately. <CHEM> R<1> and R<2> represent a variety of substituent groups; X represents a bond or an alkylene chain; and R represents a heterocyclic group. When the anti-inflammatory agent contains a carboxylic acid group, the combination with compound (I) may be in the form of a salt. |
申请公布号 |
AU4055178(A) |
申请公布日期 |
1980.04.17 |
申请号 |
AU19780040551 |
申请日期 |
1978.10.09 |
申请人 |
BEECHAM GROUP LTD. |
发明人 |
BARBARA NUNN;KEITH HOWARD BAGGALEY |
分类号 |
A61K31/425;A61K31/44;A61K31/445;A61K31/495;A61K31/535;A61K31/55;A61K31/60;A61P7/02;A61P29/00;C07D275/04 |
主分类号 |
A61K31/425 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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