| 摘要 |
Novel N-Phenethylacetamide compounds of the formula:
<CHEM>
wherein X1 represents a lower alkoxy group, X2 represents a hydrogen atom or a lower alkoxy group and R represents a phenyl group, a pyridyl group, a pyrmidinyl group or a benzoyl group, each of which may have one or more substituents selected from a halogen atom, a carbamoyl group, a lower alkoxy group, a sulfamoyl group, an amino group, a lower alkylamino group, a lower alkylthio group, a hydroxy group and a lower alkoxycarbonyl group and the pharmaceutically acceptable acid addition salts and hydrates thereof, which exhibit a distinct anti-peptic ulcer activity in human and animals are prepared e.g. by reacting a compound of the formula:
<CHEM>
wherein Z represents a halogen atom with a compound of the formula:
R-NH2
<??>Therapeutic compositions containing such amides are also described.
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