| 摘要 |
<p>PRODUCTION OF N-SUBSTITUTED OXAZOLIDINES N-substituted oxazolidines having the formula in which: a) R is C1-C10 haloalkyl, C1-C10 alkyl or lower alkylthio; R1 and R2 are independently hydrogen, C1-C12 alkyl, lower alkoxyalkyl or lower alkylol; and R3, R4, R5 and R6 are independently hydrogen, lower alkyl, lower alkoxyalkyl or lower alkylol, or in which: b) R is haloalkyl or chloroalkenyl, R1 is hydrogen, lower alkyl, phenyl, naphthyl, or substituted phenyl wherein the substituents are mono- or dichloro, nitro, methyl, methoxy or hydroxyl; R2 is hydrogen or lower alkyl; R3 is hydrogen, lower akyl, hydroxymethyl, N-methyl carbamoyloxymethyl or dichloroacetoxymethyl; R4 is hydrogen or lower alkyl; R5 is hydrogen, lower alkyl or phenyl and R6 is hydrogen; provided that at least one of R1 or R5 is phenyl, substituted phenyl or naphthyl, are prepared by reacting an oxazolidine with an acid chloride or analogous compound in the presence of a hydrogen chloride acceptor and water. The process is characterized by minimization of by-product formation.</p> |
