摘要 |
<p>Compounds of the formula wherein R is hydrogen or methoxy; R1 is hydrogen, lower alkyl, cyclo-lower alkyl, cyclo-lower alkenyl, cyclo-lower alkadienyl, thienyl, furyl, phenyl, phenyl-lower alkyl, or substituted phenyl wherein said phenyl substituent is halogen, hydroxy, amino, lower alkyl or lower alkoxy; R2 is hydrogen, lower alkyl, lower alkenyl, cyclo-lower alkyl or lower alkanoyl; R3 is hydrogen, lower alkyl, phenyl-lower alkyl, diphenyl-lower alkyl, tri(lower alkyl)silyl, a salt forming ion, or ; R5 is lower alkyl, phenyl or phenyl-lower alkyl; R6 is hydrogen or lower alkyl and R4 is a 5- or 6-membered heterocyclic ring containing carbon and 1 to 4 atoms selected from the group consisting of nitrogen, sulfur and oxygen, unsubstituted or substituted with one lower alkyl, lower alkoxy, halogen or exocyclic oxygen, are useful as antibacterial agents.</p> |