发明名称 |
2-DEOXYSTREPTAMINE AMINOGLYCOSIDES |
摘要 |
<p>Processes for the production of novel 2-deoxystrept-amine aminoglycosides by alkylation of an appropriate aminoglycoside or aminoglycoside derivative are disclosed. The compounds of the invention have an amino group on the l-position which is substituted with an alkyl group bearing one or more hydroxyl groups on carbon atoms other than those linked to the amino group. Such compounds are effective in treating bacterial infections and have been found to possess lower toxicity than many known aminoglycosides.</p> |
申请公布号 |
CA1075235(A) |
申请公布日期 |
1980.04.08 |
申请号 |
CA19770279773 |
申请日期 |
1977.06.03 |
申请人 |
PFIZER CORPORATION |
发明人 |
RICHARDSON, KENNETH;PLEWS, RHONA M.;WRIGHT, JAMES R. |
分类号 |
C07H15/234;A61K31/70;A61K31/7008;A61K31/7028;A61K31/7034;A61K31/7036;A61P31/04;C07H15/22;C07H15/236;(IPC1-7):07H15/22 |
主分类号 |
C07H15/234 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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