发明名称 TETRAPEPTIDE DERIVATIVES
摘要 Compounds of the formula <IMAGE> and pharmaceutically acceptable non-toxic acid addition salts thereof, in which L and D, when applicable, define the chirality; R1 and R2 independently are hydrogen or C1-C3 primary alkyl; R3 is C1-C4 primary or secondary alkyl or -CH2CH2-S-CH3; R4 is hydrogen or C1-C3 primary alkyl; R5 is hydrogen or C1-C3 primary alkyl; Y is hydrogen or acetyl; and Z is <IMAGE> -CH2OH, or -CN; subject to the limitation that no more than one of R4 and R5 is C1-C3 primary alkyl; are useful analgesic agents.
申请公布号 AU4024778(A) 申请公布日期 1980.04.03
申请号 AU19780040247 申请日期 1978.09.27
申请人 LILLY, E. AND COMPANY 发明人 EDWARD LEE SMITHWICK, JR.;ROBERT CURTIS ARTHUR FREDERICKSON;ROBERT THEODORE SHUMAN
分类号 C07K5/08;A61K38/07;A61K38/22;C07K1/113;C07K5/087;C07K5/10;C07K5/107;C07K14/575;C07K14/655 主分类号 C07K5/08
代理机构 代理人
主权项
地址