PROSTAGLANDIN DERIVATIVES AND PROCESS OF PREPARING THE SAME

摘要

Prostaglandin derivatives corresponding to the general formula : wherein R1 represents hydrogen, methyl or ethyl, R2, R3 and R4, which are the same or different, each represent hydrogen or methyl and R is selected from.the groups consisting of : and in which R5 represents hydrogen, methyl or ethyl, R6 represents methyl, ethyl or acetyl and R7 and R8, when they are different, each repxesent hydrogen or a branched- or straight-chain alkyl group having from 1 to 7 carbon atoms or R7 and R8, when they are identical, each represent hydrogen or a straight-chain alkyl group having from 1 to 3 carbon atoms with the provises that :- when R2,R3,R4, R7 and R8 all represent hydrogen R5 is methyl or ethyl, - when R2, R3, R4, R7 and R8 all represent hydrogen and R5 then R1 is ethyl. These prostaglandin derivatives are in the form of a mixture of isomers or of an individual isomer. They are useful in the treatment of pathological states which affect the respiratory system.