发明名称 MANUFACTURE OF BROMIDE OF ERGOT ALKALOIDS
摘要 A process for the production of a compound of formula I <IMAGE> wherein R1 is carboxyl, alkoxy- (C1-5)carbonyl, amido, alkyl(C1-5)amido, di(alkyl(C1-5))amido or an amido radical of formula II <IMAGE> wherein Ra is alkyl(C1-4), Rb is alkyl(C1-4) or benzyl, and R2 is hydrogen or alkyl(C1-4), and either R3 is hydrogen and R4 is hydrogen or alkoxy(C1-4> or R3 and R4 together are a single bond, is characterised in that a compound of formula III <IMAGE> wherein R1 to R4 are as defined above, is brominated with a bromine complex of 3-bromo-6-chloro-2-methyl- imidazo[1,2-b]pyridine having the formula IV: <IMAGE>
申请公布号 JPS5545699(A) 申请公布日期 1980.03.31
申请号 JP19790123732 申请日期 1979.09.25
申请人 SANDOZ AG 发明人 MIRIAN YURUJIEKU;RUDORUFU RIYUTSUKUMAN;BURANKO SUTANOBUNIKU;MIHA CHISURAA
分类号 C07D457/04;C07D457/06;C07D519/02;(IPC1-7):C07D457/04 主分类号 C07D457/04
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