| 摘要 |
The invention concerns compounds of the formula I <IMAGE> wherein Ph is unsubstituted 1,2-phenylene or 1,2-phenylene substituted by one to three identical or different members selected from lower alkyl, lower alkoxy, lower alkylene-dioxy, halogeno or trifluoromethyl, each of R1 and R2 is hydrogen or lower alkyl, each of R3 and R4 is hydrogen, lower alkyl or (R3 +R4) is Ph or lower alkylene separating both nitrogens by 2 to 4 carbon atoms, R5 is hydrogen, lower alkyl or HPh, X is oxo, thioxo, imino or lower alkylimino, Y is epoxy, epithio or sulfinyl, m is an integerfrom 1 to 7, each of p and q is an integer from 1 to 3, but (p+q)=4, and acid additional salts thereof. The compounds exhibit stimulant and antidepressive effects. They are prepared by reduction of corresponding amides. |
