发明名称 ANTI-INFLAMMATORY IMIDAZOLES
摘要 <p>Anti-inflammatory 4,5-diaryl-2-(substituted-thio)-imidazoles and their corresponding dulcoxides and sulfones, which are useful for treating arthritis and related diseases, are disclosed. The imidazoles are of the formula where n = 0-3; R1 is alkyl, allyl, vinyl, -CH2COCH3, CH2S(O)mCH3 where m is 0-2, mono- or polyhaloalkyl; and R2 and R3, the same or different, are where Y1 and Y2, the same or different, are hydrogen, hydroxy, alkyl and specified halogen and halogen-, nitrogen-, oxygenand/or sulfur-substituted radicals.</p>
申请公布号 CA1074327(A) 申请公布日期 1980.03.25
申请号 CA19760258690 申请日期 1976.08.09
申请人 E.I. DU PONT DE NEMOURS AND COMPANY 发明人 CHERKOFSKY, SAUL C.;SHARPE, THOMAS R.
分类号 A61K31/415;A61K31/4164;A61P29/00;C07D233/84 主分类号 A61K31/415
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