摘要 |
<p>Hydrogenolysis of the benzylidene acetal 2-phenyl-6- (1-hydroxy-2-t-butylaminoethyl)-4H-pyrido3,2-d!-1,3-dioxin to the free base, 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-t-butyl-aminoethyl)pyridine especially in the presence of water, and conversion of the base to acid addition salts, especially the acetate salt.</p> |