发明名称 Preparation of 4-hydroxymethyl-imidazole derivatives from the corresponding 4-imidazole carboxylic acid esters.
摘要 The process for preparing derivatives of formula: <IMAGE> in which R1, R2 and R3, which are identical or different, are chosen from hydrogen and alkyl radicals containing 1 to 4 carbon atoms, by reduction of the corresponding carboxylic esters, is characterised in that the reducing agent is a product chosen from trialkylaluminiums, alkylaluminium hydrides and alkoxyaluminium hydrides which may or may not contain an alkali metal atom, the said reduction reaction being carried out in a dry inert medium, and in that the product obtained is then hydrolysed with water or a water-alcohol mixture.
申请公布号 EP0008596(A1) 申请公布日期 1980.03.19
申请号 EP19780400088 申请日期 1978.09.04
申请人 DEVINTER EUROPE S.A. SOCIETE ANONYME DITE: 发明人 GIGNIER, JEAN PIERRE;BOURRELY, JACQUES
分类号 C07D233/54;C07D233/64;(IPC1-7):C07D233/64 主分类号 C07D233/54
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