PRODUCING DIURETIC AND SALURETIC EFFECTS WITH BENZOFURAN CARBOXYLIC ACID DERIVATIVES

摘要

5-(2-Bromo-2-bromomethyl-alkanoyl)-benzofuran-2-carboxylic acids and their pharmaceutically acceptable salts with bases have diuretic and saluretic activities. A typical embodiment is 5-(2-bromo-2-bromomethyl-butyryl)-6-methyl-benzofuran-2-carboxylic acid. A method of producing a diuretic and simultaneously a saluretic effect comprising administering said compounds to warm-blooded animals as well as pharmaceutical composition containing said compounds are provided.