发明名称 |
2-[[2-Methyl-1-[2-benzoyl(or benzyl)phenyl]-1H-imidazol-5-yl]methyl]-1H-isoindole-1,3(2H)-diones |
摘要 |
A multistep process is presented for the preparation of imidazobenzodiazepines of the formula <IMAGE> wherein X and Y are selected from the group consisting of hydrogen, halogen and trifluoromethyl. Also presented are novel intermediates utilized in the process. The end products are useful as sedatives, anxiolytics, muscle relaxants and anticonvulsants. The end products are especially useful in intravenous compositions for use in preoperative anesthesia.
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申请公布号 |
US4194049(A) |
申请公布日期 |
1980.03.18 |
申请号 |
US19790025219 |
申请日期 |
1979.03.29 |
申请人 |
HOFFMANN-LA ROCHE INC |
发明人 |
FIELD, GEORGE F;ZALLY, WILLIAM J |
分类号 |
C07D233/64;A01N43/90;C07C45/51;C07C47/14;C07D233/54;C07D403/06;C07D487/04;(IPC1-7):C07D403/06 |
主分类号 |
C07D233/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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