发明名称 ALKALI PROTEASE INHIBITOR
摘要 <p>PURPOSE:To provide the title novel substance having a molecular weight of about 600, by culturing novel strains. CONSTITUTION:Strains of Streptomyces nigrescens WT27 (FERM-P No.4131) are cultured in an ordinary medium at a pH of 5.0-9.0 and 15-40 deg.C aerobically to give the objective inhibitor. The product has the following properties: (1) Elementary analysis: C, 57.6%; H, 7.9%; N, 15.2%. (2) Molecular weight: about 600. (3) Melting point: 203-204 deg.C. (4) Solubility: slightly soluble in water; soluble in dimethyl solfoxide, N,N-dimethyl formamide, acetic acid, methanol, ethanol, and butanol; insoluble in ether, hexane, chloroform, and benzene. (5) Color reaction: positive to the smith, Sakaguchi, 2,4-dinitro-phenylhydrazine, and triphenyltetrazolium chloride reactions; negative to the ninhydrin and Ehrlich reactions.</p>
申请公布号 JPS5537145(A) 申请公布日期 1980.03.15
申请号 JP19780109819 申请日期 1978.09.08
申请人 AJINOMOTO KK 发明人 MURAO SAWAO;FUKUHARA KENICHI
分类号 C07G99/00;A61K35/74;A61P1/16;C12N9/00;C12N9/99;C12P1/06;C12R1/465 主分类号 C07G99/00
代理机构 代理人
主权项
地址