发明名称 |
Preparation of gamma-pyrones from 3-substituted furans |
摘要 |
Gamma-pyrones are prepared by contacting a 3-halo-furfuryl alcohol or a 3-alkoxy-furfuryl alcohol with one equivalent of a halogen, peracid or peroxide oxidant and then heating until hydrolysis of the formed 4-substituted-dihydropyran intermediate is substantially complete. Maltol (2-methyl-3-hydroxy-4H-pyran-4-one) is prepared by this process from 2(1-hydroxyethyl)-3-alkoxy furans or 2(1-hydroxyethyl)-3-halo-furans. Gamma-pyrones are also prepared by contacting the corresponding 3-substituted-2,5-dialkoxy-furfuryl alcohols with acid until conversion to the gamma-pyrones is substantially complete.
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申请公布号 |
US4191693(A) |
申请公布日期 |
1980.03.04 |
申请号 |
US19780937408 |
申请日期 |
1978.08.28 |
申请人 |
PFIZER INC |
发明人 |
BRANNEGAN, DANIEL P;BRENNAN, THOMAS M;KUHLA, DONALD E;WEEKS, PAUL D |
分类号 |
C07D309/40;(IPC1-7):C07D309/22 |
主分类号 |
C07D309/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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