发明名称 Reagent systems, enzymatic assays and compositions therefor
摘要 An improved reagent system for chemical determinations and novel compositions therefor provide improved reagent stability, particularly in a dry, storage stable phase. For determinations in which hexokinase and glucose-6-phosphate dehydrogenase are indicator enzymes, glycine and taurine are combined with bovine serum albumin to provide a bulking agent for the indicator enzymes which also acts as a stabilizer. A novel salt, the tris (hydroxymethyl)aminomethane salt of 2 mercaptosuccinic acid, acts as an activator or stabilizer in chemistries utilizing the indicator enzymes, namely determinations of creatine phosphokinase or glucose. The novel salt also acts as a stabilizer in a urea nitrogen determination. Dry reagent components are bulked in triethanolammonium terephthalate. Novel CPK, glucose and serum urea nitrogen determinations are also provided.
申请公布号 US4189536(A) 申请公布日期 1980.02.19
申请号 US19770849790 申请日期 1977.11.09
申请人 HYCEL INC 发明人 GREEN, STANLEY E
分类号 C12Q1/50;C12Q1/54;C12Q1/58;(IPC1-7):G01N31/14 主分类号 C12Q1/50
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