发明名称 TRANS-4-AMINO-3,4-DIHYDRO-2H-BENZO-E/B/-PYRAN-3-OL COMPOUNDS
摘要 <p>compounds are disclosed having blood pressure lowering activity which are of the general formula I: (I) and pharmaceutically acceptable salts thereof wherein R1 is hydrogen, an alkyl group containing 1 to carbon atoms which may be substituted with a hydroxyl group or a cyclopropylmethyl group; R2 is hydrogen or an alkyl group containing 1 to 6 carbon atoms; or-NR1R2 together represent a radical selected from pyrrolidino, piperidino, morpholino, piperazino, hexamethyleneamino, N-phenylpiperazino, heptamethyleneamino and hexamethylenetetramine wherein each of these heterocyclic groups may be substituted with 1 or 2 methyl groups; R3 is hydrogen, a nitro or amino group or amino group substituted by a lower alkyl or a lower alkanoyl group; R4 is hydrogen; or R3 together with R4 form a CH=CH-CH=CH system; and R5 and R6 are each an alkyl group containing 1 to 6 carbon atoms.</p>
申请公布号 CA1072090(A) 申请公布日期 1980.02.19
申请号 CA19750228104 申请日期 1975.05.30
申请人 BEECHAM GROUP LIMITED 发明人 WATTS, ERIC A.
分类号 A61K31/35;A61K31/352;A61K31/395;A61K31/40;A61K31/4025;A61K31/443;A61K31/445;A61K31/535;A61P9/08;A61P9/12;C07D311/68;C07D311/70;C07D311/72;C07D311/92;C07D405/04;C07D405/12;C07D493/04;(IPC1-7):07D407/04 主分类号 A61K31/35
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