发明名称 |
Novel cyclopentenone derivatives and methods for the preparation of the novel compounds. |
摘要 |
<p>Cyclopentenone compounds of formula I useful as intermediates in the preparation of certain substituted prostan-1-ols: <CHEM> and both R groups are the same and are hydrogen or the group: <CHEM> wherein R2 is(C1-C4)alkyl and R3 is hydrogen or (C1-C4) alkyl, with the proviso that Z is not -(CH2)4- when R is hydrogen. Processes for their preparation: by rearranging a substituted 2,5-dihydrofuran derivative of the formula: <CHEM> or by etherification of both OH functions in formula I with a 2-alkoxypropene of the formula <CHEM> R</p> |
申请公布号 |
EP0043479(A1) |
申请公布日期 |
1982.01.13 |
申请号 |
EP19810104760 |
申请日期 |
1979.12.14 |
申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
FLOYD, MIDDLETON BRAWNER, JR.;GRUDZINSKAS, CHARLES VINCENT;WEISS, MARTIN JOSEPH;CHEN, SOW-MEI LAI |
分类号 |
A61K31/557;A61K31/5575;A61P43/00;C07C29/10;C07C29/40;C07C33/05;C07C45/30;C07C45/45;C07C45/59;C07C45/71;C07C49/707;C07C49/743;C07C49/753;C07C67/00;C07C401/00;C07C405/00;C07D307/32;C07F7/18;C07F7/22;(IPC1-7):07C49/753;07C45/59;07C45/71;07C49/743 |
主分类号 |
A61K31/557 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|