发明名称 ALPHAAVINYLAMINO ACID AND ESTER
摘要 Novel alpha -vinyl- alpha -aminoacids having the formula <CHEM> wherein R has the signification given in the description and is H or C1-C18 alkyl, e.g. the compounds of the formulas <CHEM> are prepared e.g. by treating a derivative of the formula <CHEM> with a strong base and an alkylating agent, followed by hydrolysis. The novel aminoacids are useful for treating hypertension, as gastric secretion inhibitors, antihistamine antiallergics and antitumor agents. Furthermore, they exhibit enzyme inhibition.
申请公布号 JPS5519284(A) 申请公布日期 1980.02.09
申请号 JP19790093348 申请日期 1979.07.24
申请人 MERCK & CO INC 发明人 AASAA EE PACHIETSUTO;DEIBUITSUDO TAUBU
分类号 A61K31/195;A61K31/215;A61K31/22;A61K31/395;A61P9/12;A61P35/00;A61P37/08;A61P43/00;C07C229/30;C07C229/36;C07D209/18;C07D209/20;C07D233/54;C07D233/64;C07D317/46 主分类号 A61K31/195
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