摘要 |
Novel alpha -vinyl- alpha -aminoacids having the formula <CHEM> wherein R has the signification given in the description and is H or C1-C18 alkyl, e.g. the compounds of the formulas <CHEM> are prepared e.g. by treating a derivative of the formula <CHEM> with a strong base and an alkylating agent, followed by hydrolysis. The novel aminoacids are useful for treating hypertension, as gastric secretion inhibitors, antihistamine antiallergics and antitumor agents. Furthermore, they exhibit enzyme inhibition. |