| 摘要 |
2-[N-(2-Hydroxyethyl)-N-lower alkylamino methyl]-benzhydrols of formula <IMAGE> in which R denotes a methyl or ethyl group, X denotes a fluorine, chlorine or bromine atom or a methyl group, Y denotes a fluorine or chlorine atom or a methyl or methoxy group and m and n each denote 0, 1 or 2, are prepared by reducing a compound of formula III in the presence of an alkanoic acid with sodium borohydride in an inert solvent. The benzhydrols of formula I can be directly converted into the corresponding phenylbenz-(f)-2,5-oxazocines, which are valuable physiologically active substances. <IMAGE> |
