| 摘要 |
A nitrosourea compound of the formula: <IMAGE> wherein R1 is alkyl of one to six carbon atoms, hydroxyalkyl of one to six carbon atoms, alkenyl of three to five carbon atoms or alkynyl of three to five carbon atoms, R2 is aldopentofuranosyl, aldo-pentopyranosyl, aldo-hexopyranosyl, O-aldo-hexopyranosyl-(1->4)-aldo-hexopyranosyl or a group of the formula: -CH2(CHOH)nCH2OH, and wherein n is zero or an integer of one to four. A method of preparation is disclosed whereby said nitrosourea compound is prepared by the nitrosation of a compound of the formula: <IMAGE> wherein R1 and R2 are the same as above. Said nitrosourea compound is useful as an anti-tumor or anti-leukemic agent. |
