DIHYDROMOCIMYCIN FROM STREPTOMYCES RAMOCISSIMUS

摘要

A new antibiotic (now called dihydromocimycin) being a yellow, salt-forming weak acid and its non-toxic, pharmaceutically acceptable salts produced by the microorganism Streptomyces ramocissimus or suitable mutants thereof. The antibiotic has antibacterial properties and has been found to be effective against Treponema dysentery, one of the most common swine diseases. Dihydromocimycin may also be converted into mocimycin, which is an antibiotic which possesses interesting growthpromoting properties when added to animal feed, by a dehydrogenation agent. The dehydrogenation may be carried out with selenium dioxide, preferably in the presence of an organic solvent.