| 摘要 |
Bis-(2-ammonium-2-hydroxymethyl-1,3-propanediol)(2R-cis)-(3-methyloxir anyl)-phosphonate showing high bioavailability and tolerability is disclosed, as well as a method for preparing same from (2R-cis)-(3-methyloxiranyl)-phosphoric acid, or a salt thereof, and 2-amino-2-hydroxymethyl-1,3-propanediol, or a salt thereof. Pharmaceutical compositions containing the novel bis-phosphonate; useful for clinical forms of urinary and respiratory infections, are also disclosed. |
