发明名称 |
Optically active phenethanolamines, their formulations, use and preparation. |
摘要 |
Compounds of the formula (I): <CHEM> wherein: R1 is hydrogen or fluorine; R2 is hydrogen or hydroxy; R3 is hydrogen, hydroxy, fluorine, aminocarbonyl, methylaminocarbonyl, methoxycarbonyl or acetoxy; C and C both are asymmetric carbon atoms having * and ** the R absolute stereochemical configuration; with the limitation that at least one of R1 and R2 is hydrogen; or pharmaceutically acceptable salts thereof are extremely potent inotropic agents.
|
申请公布号 |
EP0007205(A1) |
申请公布日期 |
1980.01.23 |
申请号 |
EP19790301280 |
申请日期 |
1979.07.02 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
MILLS, JACK;SCHMIEGEL, KLAUS KURT;TUTTLE, RONALD RALPH |
分类号 |
A61K31/135;A61K31/137;A61K31/165;A61K31/215;A61K31/22;A61K31/24;A61P9/00;A61P9/04;A61P9/06;C07C51/367;C07C51/487;C07C65/32;C07C67/00;C07C213/00;C07C215/00;C07C215/20;C07C215/30;C07C215/54;C07C229/38;C07C231/00;C07C237/30;C07C243/38;C07D291/04;(IPC1-7):C07C91/16;A61K31/13;A61K31/16;A61K31/21;C07C91/30;C07C91/34;C07C93/26;C07C101/42;C07C103/28;C07C103/76 |
主分类号 |
A61K31/135 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|