| 摘要 |
<p>1. Optically active and racemic 7-oxo-PGl2 derivatives of general formula see diagramm : EP0031426,P12,F1 wherein Q represents hydrogen, a physiologically acceptable cation or C1-6 alkyl, X represents cis or trans -CH=CH-, -C-=C- or -CH2 -CH2 -, R**13 represens hydrogen, C1-4 alkanoyl, a protecting group of general formula R**7R**8R**9Si-or see diagramm : EP0031426,P12,F2 wherein R**7, R**8 and R**9, which may be indentical or different, represent C1-4 alkyl, R**10 and R**11, which may be identical or different represent hydrogen or methyl and R**12 represents methyl or ethyl, or the tetrahydropyran-2-yl group, R**4 represents hydrogen, C1-6 alkyl in the steric alpha or beta configuration, R**1 and R**2 represent hydrogen or C1-6 alkyl Y represents methylene, oxygen or -NH- and R**3 represents C1-6 alkyl or phenyl which may be monosubstituted by halogen-substituted C1-6 alkyl, hydroxyl, mercapto, C1-6 alkanoyloxy, benzoyloxy, amino, mono- or di-C1-6 alkylamino, halogen, C1-6 alkoxy or C1-6 alkylthio.</p> |
