ARTICLES PROVIDING SUSTAINED RELEASE AND METHOD OF MAKING

摘要

Articles for providing sustained release of water-soluble components. The articles comprise agglomerate particles comprising an organophobic water-soluble nucleus particle surrounded by smaller, clinging organphilic particles. The agglomerate particles are bound into a coherent mass, such as a tablet, by an organic, waterinsoluble binder. The release characteristics Or the articles can be selectively controlled by controlling the type and relative amount Or the organophilic particles employed. The articles can be made by dry-bending the solid ingredients and forming and fusing the blended mass.