摘要 |
2,4,6-Triiodobenzonitriles of the formula <IMAGE> wherein Z is a direct bond or alkylene, X is -COOH or -NR1R2 wherein R1 is H or hydrocarbon or hydroxy-hydrocarbon and R2 is lower acyl, and Y is H or -COOH, and their simple esters, amides and pharmaceutically acceptable salts, are useful as X-ray contrast agents and can be prepared by diazotizing the corresponding 2,4,6-triiodoanilines followed by reaction with a metal cyanide. |