PEPTIDES HAVING STRONG LH-RH/FSH-RH ACTIVITY AND PROCESS FOR THEIR MANUFACTURE

摘要

PEPTIDES HAVING STRONG LH-RH/FSH-RH ACTIVITY AND PROCESS FOR THEIR MANUFACTURE of the disclosure: The present invention relates to peptides having strong LH-RH/ FSH-RH activity, wherein Gly in 6-position is replaced by different substituted amino acids and in 10-position there is Glycinamide or glycin in 10-position is replaced by a NH-alkyl group with 1 - 3 carbon atoms or a NH-cyclopropyl group. The invention relates as well to a process for manufacturing said peptides, and to pharmaceutical preparations containing said peptides.