| 摘要 |
PCT No. PCT/FR92/00935 Sec. 371 Date Apr. 6, 1994 Sec. 102(e) Date Apr. 6, 1994 PCT Filed Oct. 8, 1992 PCT Pub. No. WO93/07130 PCT Pub. Date Apr. 15, 1993This invention relates to compounds having formula (I), <IMAGE> (I) wherein R1 is a hydrogen or halogen atom or an alkyl, alkoxy, alkylthio, nitro, hydroxy or cyano radical; R2 is an alkyl radical or a chain -CH(R5)-CO-R6; R3 is (a) a phenyl radical substituted by one or a plurality of substituents selected amongst the radicals -alk-SO3H, -alk-PO3H2, -CH=NOH, -CH-NO-alk-COOX, -S-alk-COOX, -SO-alk-COOX, -SO2-alk-COOX, -CH=CH-COOX, -alk-CO-NHOH, -C(=NOH)-COOX, -alk-N(OH)-CO-alk,-alk-SO2H, -CH=CH-SO3H, -C(COOX)=N-O-alk-COOX, tetrazolyalkyle or a group having a formula (I) or (b) a ring having the formula (A) <IMAGE> (A) wherein R9 is a radical =NOX, =NO-alk-COOX, =CH-COOX, -alk-COOX, -alk-SO2H or -alk-S)3H, R10 is an oxygen or sulfur atom or a methylene or alkylimino radical and R11 is a methylene or ethylene radical, R4 is a pyridyle or phenyl radical optionally substituted by one or a plurality of substituents selected amongst halogen atoms or the alkyl, alkoxy, hydroxy, carboxy, nitro and -CO-NR6 radicals, alk is an alkyl or alkylene radical and X is a hydrogen atom or an alkyl radical. The invention also discloses the salts thereof, their preparation and medicaments containing them.
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