发明名称 |
Isolation of HBsAg |
摘要 |
High purity HBsAg is injected into guinea pigs to stimulate formulation of HBsAb-positive serum. Gamma globulins containing HBsAb are separated from the serum and the globulin fraction containing HBsAb is isolated and coupled to a Sepharose gel. HBsAg from HBsAg-positive plasma is adsorbed on the gel by formation of an HBsAb-HBsAg complex. HBsAg is eluted from the column and dialysed.
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申请公布号 |
US4181713(A) |
申请公布日期 |
1980.01.01 |
申请号 |
US19780955863 |
申请日期 |
1978.10.30 |
申请人 |
MERCK & CO INC |
发明人 |
MCALEER, WILLIAM J;WASMUTH, EDWARD H |
分类号 |
A61K39/29;A61K39/00;C07K14/02;C07K16/08;(IPC1-7):A61K39/00;A61K39/12;A61K39/42 |
主分类号 |
A61K39/29 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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