| 摘要 |
A substance which inhibits the enzyme beta -lactamase, produced by a wide range of microorganisms, is obtained when species of the microorganism Micromonospora are cultivated under aerobic fermentation conditions and this inhibitor can be isolated from the fermentation medium by extraction. This substance, denominated EM4615, is useful to enhance the effectiveness of beta -lactam antibiotics such as penicillins and cephalosporins. |
