摘要 |
FIELD: pharmaceutics. SUBSTANCE: composition comprises pharmacologically active compound or its pharmaceutically acceptable substituent, aqueous-alcoholic solvent containing 15-75 vol.% of ethanol, and penetration-enhancing agent constituted by 1-alkyl-transcycloheptane-2-one containing C<SB>8-16</SB> or cis-olefin compound of formula (1) CH<SB>3</SB>(CH<SB>2</SB>)<SB>x</SB>CH = CH(CH<SB>2</SB>)<SB>y</SB>COOH, where X and Y represent each integer from 4 to 10, and sum of X and Y is equal from 10 to 16 in the amount of 0.01-5 vol.%. EFFECT: enhanced skin-penetrating capacity. 8 cl, 11 tbla
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