摘要 |
<p>NOVEL TRICYCLIC COMPOUNDS Novel tricyclic compounds of the formula: wherein A is -CH2-CH2-, -CH=CH- or , X is hydrogen, halogen, nitro, trifluoromethyl, C1-C3 alkyl or C1-C3 alkoxy, R1 and R2 are each hydrogen or C1-C4 alkyl and R4 is C1-C4 alkyl, C3-C5 alkenyl, C3-C5 alkynyl, C3-C6 cycloalkyl (C1-C3)alkyl, ar(C1-C3)alkyl, polyhalo (C1-C2)alkyl or C1-C4 alkoxy(C1-C3)alkyl and non-toxic salts thereof which are useful as antidepressants and can be prepared by reacting a compound of the formula: wherein A and X are each as defined above, with a compound of the formula: wherein R1, R2 and R4 are each as defined above and Y is halogen or sulfonyloxy, in an inert solvent in the presence of a base.</p> |